Cities need to take a systems approach if they are to develop urban infrastructure that will achieve net-zero carbon and climate-resilience goals. This report focuses on such a systems approach at the urban scale. Cities are responsible for more than 70% of global carbon dioxide emissions, with transport and buildings being among the largest contributors. Cities will also feel the greatest impact from climate change, with 70% of the global population predicted to be living in urban areas by 2050, and 95% of this urban expansion set to take place in the developing world. The report outlines case studies that provide in-depth explanation of how net-zero carbon strategies and infrastructure for climate resilience can be developed by involving all stakeholders, from companies and public institutions to the general public.