The guide of sustainable buildings in tropical regions aims to bring some answers to the environmental, economic and social issues linked to a massive urbanization process and to buildings’ design and conception methods that are often unfitted to tropical regions. It has been designed to serve as a reference for professionals of the construction sector, and more generally, of the built environment, as well as to decisions makers in the relevant areas. More globally, it aims to be a tool for teachers, lecturers and students in building design and construction. It is finally an invitation for everyone to question its professional practices and contribute to the development of more resilient, sober in resources and with low GHG emissions infrastructures. The first part of this guide focuses on designing new buildings, while the second part focuses more on refurbishing the existing building stock.